Ontology highlight
ABSTRACT:
SUBMITTER: Murthy S
PROVIDER: S-EPMC6590696 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Biological psychiatry 20190311 12
<h4>Background</h4>In humans, accumulated adverse experiences during childhood increase the risk of anxiety disorders and attention-deficit/hyperactivity disorder. In rodents, the ventral hippocampus (vHIP) is associated with anxiety regulation, and lesions in this region alter both anxiety-like behavior and activity levels. Neuronal oscillations in the vHIP of the theta frequency range (4-12 Hz) have been implicated in anxious states and derive in part from the activity of inhibitory interneuro ...[more]