Ontology highlight
ABSTRACT:
SUBMITTER: Connor JL
PROVIDER: S-EPMC6590906 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Connor Joseph L JL Minniti Caterina P CP Tisdale John F JF Hsieh Matthew M MM
The international journal of lower extremity wounds 20170109 1
Allogeneic bone marrow transplantation or peripheral blood stem cell transplantation (PBSCT) are the only curative therapies for patients with sickle cell disease (SCD). Once the patients have successfully undergone transplantation and engrafted, the hallmark of hemolytic anemia resolves, and normal hemoglobin levels are achieved. Some transplant protocols exclude patients with open wounds, including leg ulcers, because of infection risks associated with transplantation and long-term immunosuppr ...[more]