Ontology highlight
ABSTRACT:
SUBMITTER: Fatemi Nayeri M
PROVIDER: S-EPMC6590944 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Fatemi Nayeri Mahdieh M Talaei Ali A Tavakkol Afshari Jalil J Nikpoor Amin Reza AR Talaei Andisheh A Ganjali Rashin R
Reports of biochemistry & molecular biology 20190401 1
<h4>Background</h4>The pathophysiology of bipolar 1 disorder (B1D), a major psychiatric disorder with inflammatory origins and structural changes in the brain, is of great interest to researchers. Pro-inflammatory biomarkers and specific gene expression play pivotal roles in B1D development, and IFN-γ has emerged as an important inflammatory marker. The aim of this research was to determine whether the INF-γ +874 T/A polymorphism is associated with B1D susceptibility in an ethnic Iranian populat ...[more]