Ontology highlight
ABSTRACT:
SUBMITTER: Ma Z
PROVIDER: S-EPMC6592248 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Ma Zhengmin Z Jin Xinxin X Qian Zhuang Z Li Fang F Xu Mao M Zhang Ying Y Kang Xiaomin X Li Huixia H Gao Xin X Zhao Liting L Zhang Zhuanmin Z Zhang Yan Y Wu Shufang S Sun Hongzhi H
Cell cycle (Georgetown, Tex.) 20190526 13
Several studies have demonstrated the core circadian rhythm gene Bmal1 could regulate the clock control genes (CCGs) expression and maintain the integrity in cartilage tissue. In addition, its abnormal expression is connected with the occurrence and development of several diseases including osteoarthritis (OA). However, the relationship between Bmal1 and cartilage development still needs to be fully elucidated. Here, we bred tamoxifen-induced cartilage-specific knockout mice to learn the effects ...[more]