Ontology highlight
ABSTRACT:
SUBMITTER: van Dongen JA
PROVIDER: S-EPMC6593768 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
van Dongen Joris A JA Getova Vasilena V Brouwer Linda A LA Liguori Gabriel R GR Sharma Prashant K PK Stevens Hieronymus P HP van der Lei Berend B Harmsen Martin C MC
Journal of tissue engineering and regenerative medicine 20190415 6
Fat grafting is an established clinical intervention to promote tissue repair. The role of the fat's extracellular matrix (ECM) in regeneration is largely neglected. We investigated in vitro the use of human adipose tissue-derived ECM hydrogels as release platform for factors secreted by adipose-derived stromal cells (ASCs). Lipoaspirates from nondiabetic and diabetic donors were decellularized. Finely powdered acellular ECM was evaluated for cell remainders and DNA content. Acellular ECM was di ...[more]