Magnetic resonance elastography of skeletal muscle deep tissue injury.

ABSTRACT: The current state-of-the-art diagnosis method for deep tissue injury in muscle, a subcategory of pressure ulcers, is palpation. It is recognized that deep tissue injury is frequently preceded by altered biomechanical properties. A quantitative understanding of the changes in biomechanical properties preceding and during deep tissue injury development is therefore highly desired. In this paper we quantified the spatial-temporal changes in mechanical properties upon damage development and recovery in a rat model of deep tissue injury. Deep tissue injury was induced in nine rats by two hours of sustained deformation of the tibialis anterior muscle. Magnetic resonance elastography (MRE), T₂ -weighted, and T₂ -mapping measurements were performed before, directly after inde

SUBMITTER: Nelissen JL 

PROVIDER: S-EPMC6593838 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature