Ontology highlight
ABSTRACT:
SUBMITTER: Philis-Tsimikas A
PROVIDER: S-EPMC6593861 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Philis-Tsimikas Athena A Billings Liana K LK Busch Robert R Portillo Cristobal Morales CM Sahay Rakesh R Halladin Natalie N Eggert Sarah S Begtrup Kamilla K Harris Stewart S
Diabetes, obesity & metabolism 20190404 6
<h4>Aim</h4>To investigate the efficacy and safety of insulin degludec/liraglutide (IDegLira) versus insulin glargine 100 units/mL (IGlar U100) as add-on to sodium-glucose co-transporter-2 (SGLT2) inhibitor therapy.<h4>Materials and methods</h4>In this 26-week, phase IIIb, open-label, parallel-group, treat-to-target trial, conducted at 74 sites in 11 countries, insulin-naïve people aged ≥18 years with glycated haemoglobin (HbA1c) 53-97 mmol/mol (7.0-11.0%), body mass index 20-40 kg/m<sup>2</sup> ...[more]