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Physiological Predictors of Weight Regain at 1-Year Follow-Up in Weight-Reduced Adults with Obesity.


ABSTRACT: OBJECTIVE:This study aimed to assess whether changes in resting metabolic rate (RMR), exercise-induced energy expenditure (EIEE), and appetite following weight loss (WL) are associated with weight regain at 1 year. METHODS:Thirty-six adults with obesity underwent 8 weeks of a very-low-energy diet, followed by 4 weeks of refeeding and a 1-year maintenance program. RMR, EIEE, appetite ratings, and active ghrelin, peptide YY, glucagon-like peptide-1, cholecystokinin, and insulin concentrations were measured at baseline, week 13, and 1 year. RESULTS:A 17% WL (-20?±?5 kg [mean?±?SD]; range: -11.7 to -32.2 kg; P?

SUBMITTER: Nymo S 

PROVIDER: S-EPMC6593985 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Physiological Predictors of Weight Regain at 1-Year Follow-Up in Weight-Reduced Adults with Obesity.

Nymo Siren S   Coutinho Silvia R SR   Rehfeld Jens F JF   Truby Helen H   Kulseng Bård B   Martins Catia C  

Obesity (Silver Spring, Md.) 20190420 6


<h4>Objective</h4>This study aimed to assess whether changes in resting metabolic rate (RMR), exercise-induced energy expenditure (EIEE), and appetite following weight loss (WL) are associated with weight regain at 1 year.<h4>Methods</h4>Thirty-six adults with obesity underwent 8 weeks of a very-low-energy diet, followed by 4 weeks of refeeding and a 1-year maintenance program. RMR, EIEE, appetite ratings, and active ghrelin, peptide YY, glucagon-like peptide-1, cholecystokinin, and insulin conc  ...[more]

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