Ontology highlight
ABSTRACT:
SUBMITTER: Franks PW
PROVIDER: S-EPMC6594151 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Current opinion in genetics & development 20180220
Type 2 diabetes (T2D) is widespread, affecting the health of hundreds of millions worldwide. The disease results from the complex interplay of lifestyle factors acting on a backdrop of inherited DNA risk variants. Detecting and understanding biomarkers, whether genotypes or other downstream biological features that dictate a person's phenotypic response to different lifestyle exposures, may have tremendous utility in the prevention of T2D. Here, we explore (i) evidence of how human genetic adapt ...[more]