Dataset Information

Acute and one year outcome of premature ventricular contraction ablation guided by contact force and automated pacemapping software.

ABSTRACT:

Background

Radiofrequency (RF) ablation is a well-established approach to treat premature ventricular contractions (PVC) and is associated with good outcomes.

Aim

The present study sought to analyze the acute efficacy and 1-year outcomes of PVC ablation using RF technology with an approach based on automated pace-mapping and contact force (CF) information.

Methods

Sixty-one consecutive patients (52.4% males, age 45.9 ± 12.5) underwent catheter ablation for symptomatic monomorphic PVC. All procedures were guided by a 3-dimensional mapping system; site of ablation was selected based on PASO^™ aided pace-mapping; RF was started on the selected location when stable catheter position with >10 g of CF were obtained.The procedure was defined as acutely effective if the PVC was eliminated and it did not recur during within 30 minutes. Long-term efficacy was defined as a decrease by more than 95% at 1 year of the initial PVC burden at ECG Holter monitoring.

Results

The PVC ablation was performed in the right ventricular outflow tract in 37 patients (60.7%), left ventricle in 15 patients (24.6%), coronary cusps in 6 patients (9.8%), right ventricle in 3 patients (4.9%); PVC ablation was acutely successful in 59 of patients (96.7%). At 1-year efficacy was obtained in 57 patients (93.4%). No major complications occurred. Mean procedural and fluoroscopy time were 94.5 ± 20.9 and 4.3 ± 2.5 minutes respectively.

Conclusion

Premature ventricular contraction RF ablation mainly guided by PASO^™ and CF showed high success rate in both acute and 1-year follow-up (96.7% and 93.4% respectively). The best efficacy cut-off for RF ablation of PVCs has been identified in presence of both PASO^™ ?95% and CF >10 g.

SUBMITTER: Capulzini L

PROVIDER: S-EPMC6595285 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Publications

Acute and one year outcome of premature ventricular contraction ablation guided by contact force and automated pacemapping software.

Capulzini Lucio L Vergara Pasquale P Mugnai Giacomo G Salghetti Francesca F Abugattas Juan Pablo JP El Bouchaibi Said S Iacopino Saverio S Sieira Juan J Enriquez Coutiño Hugo H Ströker Erwin E Brugada Pedro P Chierchia Gianbattista G de Asmundis Carlo C

Journal of arrhythmia 20190514 3

<h4>Background</h4>Radiofrequency (RF) ablation is a well-established approach to treat premature ventricular contractions (PVC) and is associated with good outcomes.<h4>Aim</h4>The present study sought to analyze the acute efficacy and 1-year outcomes of PVC ablation using RF technology with an approach based on automated pace-mapping and contact force (CF) information.<h4>Methods</h4>Sixty-one consecutive patients (52.4% males, age 45.9 ± 12.5) underwent catheter ablation for symptomatic monom ...[more]

PMID: 31293706

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Project description:IntroductionAblation Index, also known as VISITAG SURPOINT™, is a novel lesion-quality marker that improves outcomes in radiofrequency (RF) catheter ablation of atrial fibrillation (AF). There is no direct evidence on the comparative effectiveness of RF ablation with Ablation Index and cryoballoon (CB). The objective of the present study was to conduct a matching-adjusted indirect comparison (MAIC) using individual patient-level data (IPD) to compare the effectiveness of RF ablation with Ablation Index to that of CB on recurrence of atrial arrhythmias 12 months after catheter ablation in patients with paroxysmal AF (PAF).MethodsIndividual patient-level data for RF ablation with Ablation Index were obtained from two studies: Solimene et al. [J Interv Card Electrophysiol 54(1):9-15, 2019] and Hussein et al. [J Cardiovasc Electrophysiol 28(9):1037-1047, 2017]. Comparable CB studies identified from a systematic literature review were pooled. Prognostic variables for adjustment were ranked a priori by several practicing electrophysiologists. In the absence of a common treatment arm between the Ablation Index and CB studies, an unanchored MAIC was conducted. Primary analysis compared the Solimene et al. study to pooled CB studies. A secondary analysis compared pooled RF ablation with Ablation Index studies to pooled CB studies. Several scenario and sensitivity analyses were conducted.ResultsPrimary analyses showed statistically significant reductions in the rate of arrhythmia recurrence with RF ablation with Ablation Index compared to CB in unmatched, unadjusted (HR 0.50, 95% CI 0.27-0.95) and matched (0.42, 0.21-0.86) analyses. Greater reductions in the rate of arrhythmia recurrence that favored RF ablation with Ablation Index were observed after matching and adjusting for age (0.41, 0.20-0.85), age and left ventricular ejection fraction (0.37, 0.16-0.88), and age, sex, and left ventricular ejection fraction (0.30, 0.13-0.71). Secondary and sensitivity analyses showed similar reductions.ConclusionsRadiofrequency ablation with Ablation Index was associated with reductions in recurrence of atrial arrhythmias at 12 months compared to CB in unmatched and unadjusted, matched, and matched and adjusted comparisons.

Dataset Information

Acute and one year outcome of premature ventricular contraction ablation guided by contact force and automated pacemapping software.

Background

Aim

Methods

Results

Conclusion

Publications

Acute and one year outcome of premature ventricular contraction ablation guided by contact force and automated pacemapping software.

Similar Datasets

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