Etiology, cancer stem cells and potential diagnostic biomarkers for esophageal cancer.
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ABSTRACT:
SUBMITTER: Liu K
PROVIDER: S-EPMC6597177 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Publications
Etiology, cancer stem cells and potential diagnostic biomarkers for esophageal cancer.
Liu Kuancan K Zhao Tingting T Wang Junkai J Chen Yunyun Y Zhang Rui R Lan Xiaopeng X Que Jianwen J
Cancer letters 20190521
Esophageal cancer (EC) has been a leading cause of cancer death worldwide in part due to late detection and lack of precision treatment. EC includes two major malignancies, esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC). Recent studies reveal that ESCC and EAC have distinct cell of origin and contain cancer stem cells (also known as tumor initiating cells) expressing different cell surface markers. These biomarkers have potentially important values for both early d ...[more]
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