The ENCODE Blacklist: Identification of Problematic Regions of the Genome.
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ABSTRACT:
SUBMITTER: Amemiya HM
PROVIDER: S-EPMC6597582 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
The ENCODE Blacklist: Identification of Problematic Regions of the Genome.
Amemiya Haley M HM Kundaje Anshul A Boyle Alan P AP
Scientific reports 20190627 1
Functional genomics assays based on high-throughput sequencing greatly expand our ability to understand the genome. Here, we define the ENCODE blacklist- a comprehensive set of regions in the human, mouse, worm, and fly genomes that have anomalous, unstructured, or high signal in next-generation sequencing experiments independent of cell line or experiment. The removal of the ENCODE blacklist is an essential quality measure when analyzing functional genomics data. ...[more]
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