RNA-protein interactions: disorder, moonlighting and junk contribute to eukaryotic complexity.
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ABSTRACT:
SUBMITTER: Balcerak A
PROVIDER: S-EPMC6597761 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
RNA-protein interactions: disorder, moonlighting and junk contribute to eukaryotic complexity.
Balcerak Anna A Trebinska-Stryjewska Alicja A Konopinski Ryszard R Wakula Maciej M Grzybowska Ewa Anna EA
Open biology 20190619 6
RNA-protein interactions are crucial for most biological processes in all organisms. However, it appears that the complexity of RNA-based regulation increases with the complexity of the organism, creating additional regulatory circuits, the scope of which is only now being revealed. It is becoming apparent that previously unappreciated features, such as disordered structural regions in proteins or non-coding regions in DNA leading to higher plasticity and pliability in RNA-protein complexes, are ...[more]
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