Ontology highlight
ABSTRACT:
SUBMITTER: Regalado-Reyes M
PROVIDER: S-EPMC6598029 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Regalado-Reyes Mamen M Furcila Diana D Hernández Félix F Ávila Jesús J DeFelipe Javier J León-Espinosa Gonzalo G
Journal of Alzheimer's disease : JAD 20190101 1
Despite extensive studies regarding tau phosphorylation progression in both human Alzheimer's disease cases and animal models, the molecular and structural changes responsible for neurofibrillary tangle development are still not well understood. Here, by using the antibodies AT100 (recognizes tau protein phosphorylated at Thr212 and Ser214 in the proline-rich region) and pS396 (recognizes tau protein phosphorylated at serine residue 396 in the C-terminal region), we examined phospho-tau immunost ...[more]