Dataset Information

Autofocals: Evaluating gaze-contingent eyeglasses for presbyopes.

ABSTRACT: As humans age, they gradually lose the ability to accommodate, or refocus, to near distances because of the stiffening of the crystalline lens. This condition, known as presbyopia, affects nearly 20% of people worldwide. We design and build a new presbyopia correction, autofocals, to externally mimic the natural accommodation response, combining eye tracker and depth sensor data to automatically drive focus-tunable lenses. We evaluated 19 users on visual acuity, contrast sensitivity, and a refocusing task. Autofocals exhibit better visual acuity when compared to monovision and progressive lenses while maintaining similar contrast sensitivity. On the refocusing task, autofocals are faster and, compared to progressives, also significantly more accurate. In a separate study, a majority of 23 of 37 users ranked autofocals as the best correction in terms of ease of refocusing. Our work demonstrates the superiority of autofocals over current forms of presbyopia correction and could affect the lives of millions.

SUBMITTER: Padmanaban N

PROVIDER: S-EPMC6598771 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Publications

Autofocals: Evaluating gaze-contingent eyeglasses for presbyopes.

Padmanaban Nitish N Konrad Robert R Wetzstein Gordon G

Science advances 20190628 6

As humans age, they gradually lose the ability to accommodate, or refocus, to near distances because of the stiffening of the crystalline lens. This condition, known as presbyopia, affects nearly 20% of people worldwide. We design and build a new presbyopia correction, autofocals, to externally mimic the natural accommodation response, combining eye tracker and depth sensor data to automatically drive focus-tunable lenses. We evaluated 19 users on visual acuity, contrast sensitivity, and a refoc ...[more]

PMID: 31259239

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Project description:Background: The pupillary light reflex is weaker for stimuli presented inside as compared to outside absolute scotomas. Pupillograph perimetry could thus be an objective measure of impaired visual processing. However, the diagnostic accuracy in detecting scotomas has remained unclear. We quantitatively investigated the accuracy of a novel form of pupil perimetry. Methods: The new perimetry method, termed gaze-contingent flicker pupil perimetry, consists of the repetitive on, and off flickering of a bright disk (2 hz; 320 cd/m2; 4° diameter) on a gray background (160 cd/m2) for 4 seconds per stimulus location. The disk evokes continuous pupil oscillations at the same rate as its flicker frequency, and the oscillatory power of the pupil reflects visual sensitivity. We monocularly presented the disk at a total of 80 locations in the central visual field (max. 15°). The location of the flickering disk moved along with gaze to reduce confounds of eye movements (gaze-contingent paradigm). The test lasted ~5 min per eye and was performed on 7 patients with cerebral visual impairment (CVI), 8 patients with primary open angle glaucoma (age >45), and 14 healthy, age/gender-matched controls. Results: For all patients, pupil oscillation power (FFT based response amplitude to flicker) was significantly weaker when the flickering disk was presented in the impaired as compared to the intact visual field (CVI: 12%, AUC = 0.73; glaucoma: 9%, AUC = 0.63). Differences in power values between impaired and intact visual fields of patients were larger than differences in power values at corresponding locations in the visual fields of the healthy control group (CVI: AUC = 0.95; glaucoma: AUC = 0.87). Pupil sensitivity maps highlighted large field scotomas and indicated the type of visual field defect (VFD) as initially diagnosed with standard automated perimetry (SAP) fairly accurately in CVI patients but less accurately in glaucoma patients. Conclusions: We provide the first quantitative and objective evidence of flicker pupil perimetry's potential in detecting CVI-and glaucoma-induced VFDs. Gaze-contingent flicker pupil perimetry is a useful form of objective perimetry and results suggest it can be used to assess large VFDs with young CVI patients whom are unable to perform SAP.

Dataset Information

Autofocals: Evaluating gaze-contingent eyeglasses for presbyopes.

Publications

Autofocals: Evaluating gaze-contingent eyeglasses for presbyopes.

Similar Datasets

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