Ontology highlight
ABSTRACT:
SUBMITTER: Tanase DM
PROVIDER: S-EPMC6600439 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Tanase Daniela Maria DM Radu Smaranda S Al Shurbaji Sinziana S Baroi Genoveva Livia GL Florida Costea Claudia C Turliuc Mihaela Dana MD Ouatu Anca A Floria Mariana M
International journal of molecular sciences 20190528 11
The incidence of heart failure with preserved ejection fraction (HFpEF) is increasing and its challenging diagnosis and management combines clinical, imagistic and biological data. Natriuretic peptides (NPs) are hormones secreted in response to myocardial stretch that, by increasing cyclic guanosine monophosphate (cGMP), counteract myocardial fibrosis and hypertrophy, increase natriuresis and determine vasodilatation. While their role in HFpEF is controversial, most authors focused on b-type nat ...[more]