The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia.
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ABSTRACT:
SUBMITTER: Apicella C
PROVIDER: S-EPMC6600551 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia.
Apicella Clara C Ruano Camino S M CSM Méhats Céline C Miralles Francisco F Vaiman Daniel D
International journal of molecular sciences 20190611 11
In this review, we comprehensively present the function of epigenetic regulations in normal placental development as well as in a prominent disease of placental origin, preeclampsia (PE). We describe current progress concerning the impact of DNA methylation, non-coding RNA (with a special emphasis on long non-coding RNA (lncRNA) and microRNA (miRNA)) and more marginally histone post-translational modifications, in the processes leading to normal and abnormal placental function. We also explore t ...[more]
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