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An atypical cause of myocardial infarction: case report of an obstructing papillary fibroelastoma of the aortic valve.


ABSTRACT:

Background

Papillary fibroelastomas are rare primary cardiac tumours with a prevalence of 0.01% at autopsy. They are histologically benign tumours but have been demonstrated through case series to confer an increased risk of thrombo-embolism resulting in: transient ischaemic attack, stroke, myocardial infarction, and pulmonary and systemic embolization.

Case summary

A 54-year-old woman presented with central chest pain radiating to her left arm. At presentation there was a significant troponin rise; initial high-sensitivity troponin-I (hsTn-I) 660?pg/mL increased to 3340?pg/mL at 6 h. Coronary angiogram did not reveal any obstructing coronary artery disease. Echocardiography revealed a rounded, mobile mass on the left coronary cusp of the aortic valve suspicious for papillary fibroelastoma. The patient underwent shave excision of the lesion. Intra-operatively it was noted that the mass intermittently sat within the ostium of the left main resulting in its occlusion. Histology confirmed a papillary fibroelastoma.

Discussion

Primary cardiac tumours are rare but can cause life-threatening complications such as stroke, myocardial infarction, and cardiac arrest. In the literature, the mechanism of these complications is mainly attributed to thrombo-embolism. This case demonstrates the utility of echocardiogram in investigating and diagnosing a rare cause of myocardial infarction and highlights an unusual mechanism, that is tumour causing obstruction of the coronary ostium.

SUBMITTER: Logan N 

PROVIDER: S-EPMC6601164 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Publications

An atypical cause of myocardial infarction: case report of an obstructing papillary fibroelastoma of the aortic valve.

Logan Niamh N   Islam Mohammad Sirajul MS   Chughtai Jehan Zeb JZ   Murphy Niamh F NF  

European heart journal. Case reports 20190601 2


<h4>Background</h4>Papillary fibroelastomas are rare primary cardiac tumours with a prevalence of 0.01% at autopsy. They are histologically benign tumours but have been demonstrated through case series to confer an increased risk of thrombo-embolism resulting in: transient ischaemic attack, stroke, myocardial infarction, and pulmonary and systemic embolization.<h4>Case summary</h4>A 54-year-old woman presented with central chest pain radiating to her left arm. At presentation there was a signifi  ...[more]

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