Ontology highlight
ABSTRACT:
SUBMITTER: Damre M
PROVIDER: S-EPMC6602572 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Damre Mangesh M Marchetto Alessandro A Giorgetti Alejandro A
Nucleic acids research 20190701 W1
Atomistic molecular dynamics simulations of membrane proteins have been shown to be extremely useful for characterizing the molecular features underlying their function, but require high computational power, limiting the understanding of complex events in membrane proteins, e.g. ion channels gating, GPCRs activation. To overcome this issue, it has been shown that coarse-grained approaches, although requiring less computational power, are still capable of correctly describing molecular events und ...[more]