Ontology highlight
ABSTRACT:
SUBMITTER: Lulla PD
PROVIDER: S-EPMC6602906 | biostudies-literature | 2019 May/Jun
REPOSITORIES: biostudies-literature
Lulla Premal D PD Mamonkin Maksim M Brenner Malcolm K MK
Cancer journal (Sudbury, Mass.) 20190501 3
Refractory and relapsed acute myeloid leukemia (AML) and T-lineage leukemia have poor prognosis and limited therapeutic options. Adoptive cellular immunotherapies are emerging as an effective treatment for patients with chemotherapy refractory hematological malignancies. Indeed, the use of unselected donor lymphocyte infusions has demonstrated successes in treating patients with AML and T-lineage leukemia post-allogeneic transplantation. The development of ex vivo manipulation techniques such as ...[more]