Evaluation of USPSTF Lung Cancer Screening Guidelines Among African American Adult Smokers.

ABSTRACT: Importance:The United States Preventive Services Task Force (USPSTF) recommends low-dose computed tomography screening for lung cancer. However, USPSTF screening guidelines were derived from a study population including only 4% African American smokers, and racial differences in smoking patterns were not considered. Objective:To evaluate the diagnostic accuracy of USPSTF lung cancer screening eligibility criteria in a predominantly African American and low-income cohort. Design, Setting, and Participants:The Southern Community Cohort Study prospectively enrolled adults visiting community health centers across 12 southern US states from March 25, 2002, through September 24, 2009, and followed up for cancer incidence through December 31, 2014. Participants included African American and white current and former smokers aged 40 through 79 years. Statistical analysis was performed from May 11, 2016, to December 6, 2018. Exposures:Self-reported race, age, and smoking history. Cumulative exposure smoking histories encompassed most recent follow-up questionnaires. Main Outcomes and Measures:Incident lung cancer cases assessed for eligibility for lung cancer screening using USPSTF criteria. Results:Among 48?364 ever smokers, 32?463 (67%) were African American and 15?901 (33%) were white, with 1269 incident lung cancers identified. Among all 48?364 Southern Community Cohort Study participants, 5654 of 32?463 African American smokers (17%) were eligible for USPSTF screening compared with 4992 of 15?901 white smokers (31%) (P?

SUBMITTER: Aldrich MC 

PROVIDER: S-EPMC6604090 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature