Predicting development of adolescent drinking behaviour from whole brain structure at 14 years of age.
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ABSTRACT:
SUBMITTER: Kuhn S
PROVIDER: S-EPMC6606021 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Publications
Predicting development of adolescent drinking behaviour from whole brain structure at 14 years of age.
Kühn Simone S Mascharek Anna A Banaschewski Tobias T Bodke Arun A Bromberg Uli U Büchel Christian C Quinlan Erin Burke EB Desrivieres Sylvane S Flor Herta H Grigis Antoine A Garavan Hugh H Gowland Penny A PA Heinz Andreas A Ittermann Bernd B Martinot Jean-Luc JL Nees Frauke F Papadopoulos Orfanos Dimitri D Paus Tomas T Poustka Luise L Millenet Sabina S Fröhner Juliane H JH Smolka Michael N MN Walter Henrik H Whelan Robert R Schumann Gunter G Lindenberger Ulman U Gallinat Jürgen J
eLife 20190702
Adolescence is a common time for initiation of alcohol use and development of alcohol use disorders. The present study investigates neuroanatomical predictors for trajectories of future alcohol use based on a novel voxel-wise whole-brain structural equation modeling framework. In 1814 healthy adolescents of the IMAGEN sample, the Alcohol Use Disorder Identification Test (AUDIT) was acquired at three measurement occasions across five years. Based on a two-part latent growth curve model, we conduc ...[more]
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