Cost-Effectiveness Analysis of Descemet's Membrane Endothelial Keratoplasty Versus Descemet's Stripping Endothelial Keratoplasty in the United States.

ABSTRACT:

Purpose

To determine the cost-effectiveness of Descemet's membrane endothelial keratoplasty (DMEK) compared with Descemet's stripping automated endothelial keratoplasty (DSAEK) in the United States.

Design

Cost-effectiveness analysis in a surgical center in the United States.

Participants

Binocular adult patient undergoing endothelial keratoplasty.

Methods

A base case of a 70-year-old man undergoing his first endothelial keratoplasty for bilateral Fuchs endothelial dystrophy. The cost-effectiveness of DMEK was compared with DSAEK over a 15-year time horizon. The incidences and costs of complications were derived from PubMed English literature searches, Medicare reimbursements, and average wholesale prices. All costs were discounted 3% per annum and adjusted for

SUBMITTER: Gibbons A 

PROVIDER: S-EPMC6606558 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature