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Unlocking Nanocarriers for the Programmed Release of Antimalarial Drugs.

ABSTRACT: A programmable release system with wide range of release profiles of the antimalarial artemisone (ART) from fibrous nanocarriers (NFN) is presented. This is achieved following a new paradigm of using ART-loaded NFN in infusion system of hydrophobic drug eluting nanocarriers, adapted to clinical applications. Very importantly, under these conditions ART did not degrade as it was observed in solution.

SUBMITTER: Bagheri AR 

PROVIDER: S-EPMC6607132 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Unlocking Nanocarriers for the Programmed Release of Antimalarial Drugs.

Bagheri Amir Reza AR   Agarwal Seema S   Golenser Jacob J   Greiner Andreas A  

Global challenges (Hoboken, NJ) 20170130 2

<b>A programmable release system</b> with wide range of release profiles of the antimalarial artemisone (ART) from fibrous nanocarriers (NFN) is presented. This is achieved following a new paradigm of using ART-loaded NFN in infusion system of hydrophobic drug eluting nanocarriers, adapted to clinical applications. Very importantly, under these conditions ART did not degrade as it was observed in solution. ...[more]

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