Ontology highlight
ABSTRACT:
SUBMITTER: Woo J
PROVIDER: S-EPMC6607449 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Woo Jun J Winterhoff Boris J BJ Starr Timothy K TK Aliferis Constantin C Wang Jinhua J
Life science alliance 20190702 4
Recent single-cell transcriptomic studies revealed new insights into cell-type heterogeneities in cellular microenvironments unavailable from bulk studies. A significant drawback of currently available algorithms is the need to use empirical parameters or rely on indirect quality measures to estimate the degree of complexity, i.e., the number of subgroups present in the sample. We fill this gap with a single-cell data analysis procedure allowing for unambiguous assessments of the depth of hetero ...[more]