Ontology highlight
ABSTRACT:
SUBMITTER: Battaglin F
PROVIDER: S-EPMC6607986 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Cancer management and research 20190628
Panitumumab is a fully human monoclonal antibody targeting the epidermal growth factor receptor (EGFR). It is currently approved for the treatment of <i>RAS</i> wild-type (WT) metastatic colorectal cancer (mCRC) in combination with chemotherapy in first- and second-line and as monotherapy in chemorefractory patients. This review will provide an overview of main efficacy data on panitumumab from its early development up to latest evidences, including novel perspectives on predictive biomarkers of ...[more]