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Real-world electronic health record identifies antimalarial underprescribing in patients with lupus nephritis.


ABSTRACT: Antimalarials (AMs) reduce disease activity and improve survival in patients with systemic lupus erythematosus (SLE), but studies have reported low AM prescribing frequencies. Using a real-world electronic health record cohort, we examined if patient or provider characteristics impacted AM prescribing. We identified 977 SLE cases, 94% of whom were ever prescribed an AM. Older patients and patients with SLE nephritis were less likely to be on AMs. Current age (odds ratio?=?0.97, p?

SUBMITTER: Xiong WW 

PROVIDER: S-EPMC6609095 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Real-world electronic health record identifies antimalarial underprescribing in patients with lupus nephritis.

Xiong W W WW   Boone J B JB   Wheless L L   Chung C P CP   Crofford L J LJ   Barnado A A  

Lupus 20190612 8


Antimalarials (AMs) reduce disease activity and improve survival in patients with systemic lupus erythematosus (SLE), but studies have reported low AM prescribing frequencies. Using a real-world electronic health record cohort, we examined if patient or provider characteristics impacted AM prescribing. We identified 977 SLE cases, 94% of whom were ever prescribed an AM. Older patients and patients with SLE nephritis were less likely to be on AMs. Current age (odds ratio = 0.97, <i>p</i> < 0.01)  ...[more]

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