Ontology highlight
ABSTRACT:
SUBMITTER: Rinkenberger N
PROVIDER: S-EPMC6609484 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Rinkenberger Nicholas N Schoggins John W JW
Virology 20190425
Zika virus (ZIKV) is an emerging pathogen with global health and economic impacts. ZIKV circulates as two major lineages, Asian or African. The Asian lineage has recently been associated with significant disease in humans. Numerous studies have revealed differences between African and Asian ZIKV strains with respect to cellular infectivity, pathogenesis, and immune activation. Less is known about the mechanism of ZIKV entry and whether viral entry differs between strains. Here, we characterized ...[more]