Ontology highlight
ABSTRACT:
SUBMITTER: Zhong C
PROVIDER: S-EPMC6609836 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Zhong Cuncong C Zhang Shaojie S
iScience 20190529
MicroRNA (miRNA) trans-regulates the stability of many mRNAs and controls their expression levels. Reconstruction of the miRNA-mRNA interactome is key to the understanding of the miRNA regulatory network and related biological processes. However, existing miRNA target prediction methods are limited to canonical miRNA-mRNA interactions and have high false prediction rates. Other experimental methods are low throughput and cannot be used to probe genome-wide interactions. To address this challenge ...[more]