Ontology highlight
ABSTRACT:
SUBMITTER: Zhang KW
PROVIDER: S-EPMC6609907 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Zhang Kathleen W KW Stockerl-Goldstein Keith E KE Lenihan Daniel J DJ
JACC. Basic to translational science 20190624 3
Cardiac amyloidosis is a restrictive cardiomyopathy that results from the deposition of misfolded light chain or transthyretin proteins, most commonly, in cardiac tissue. Traditionally, treatment options for light chain (AL) and transthyretin (ATTR) amyloidosis have been limited. However, there are now multiple novel therapeutics in development and several therapeutics recently approved that promise to revolutionize clinical management of AL and ATTR. Most of these agents disrupt specific stages ...[more]