Ontology highlight
ABSTRACT:
SUBMITTER: Chen Wongworawat Y
PROVIDER: S-EPMC6611013 | biostudies-literature | 2019 Jan-Dec
REPOSITORIES: biostudies-literature
Chen Wongworawat Yan Y Jack Daniel D Inman Jared C JC Abdelhalim Fouad F Cobb Camilla C Zuppan Craig William CW Raza Anwar A
Clinical pathology (Thousand Oaks, Ventura County, Calif.) 20190101
Cherubism is a rare benign autosomal dominant disorder characterized by progressive, painless, bilateral enlargement of the mandible and/or maxilla because of bone replacement by fibrotic stromal cells and osteoclast-like cells forming multilocular cysts. The lesions typically stabilize and regress after puberty. We present a 14-year-old male with severe familial cherubism. Bilateral mandibular enlargement began around age 4 and progressed until puberty, affecting his speech and mastication with ...[more]