Evaluation of the predictive value of the bleeding prediction score VTE-BLEED for recurrent venous thromboembolism.

ABSTRACT:

Introduction

VTE-BLEED is a validated score for identification of patients at increased risk of major bleeding during extended anticoagulation for venous thromboembolism (VTE). It is unknown whether VTE-BLEED high-risk patients also have an increased risk for recurrent VTE, which would limit the potential usefulness of the score.

Methods

This was a post hoc analysis of the randomized, double-blind, placebo-controlled PADIS-PE trial that randomized patients with a first unprovoked pulmonary embolism (PE) initially treated during 6 months to receive an additional 18-month of warfarin vs. placebo. The primary outcome of this analysis was recurrent VTE during 2-year follow-up after anticoagulant discontinuation, that is, after the initial 6-month treatment in the placebo arm and

SUBMITTER: Klok FA 

PROVIDER: S-EPMC6611364 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature