Ontology highlight
ABSTRACT:
SUBMITTER: Neochoritis CG
PROVIDER: S-EPMC6611686 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Science advances 20190705 7
The compatibility of free boronic acid building blocks in multicomponent reactions to readily create large libraries of diverse and complex small molecules was investigated. Traditionally, boronic acid synthesis is sequential, synthetically demanding, and time-consuming, which leads to high target synthesis times and low coverage of the boronic acid chemical space. We have performed the synthesis of large libraries of boronic acid derivatives based on multiple chemistries and building blocks usi ...[more]