Ontology highlight
ABSTRACT:
SUBMITTER: Moghadasi Boroujeni S
PROVIDER: S-EPMC6611768 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Moghadasi Boroujeni Samaneh S Koontz Alison A Tseropoulos Georgios G Kerosuo Laura L Mehrotra Pihu P Bajpai Vivek K VK Selvam Surya Rajan SR Lei Pedro P Bronner Marianne E ME Andreadis Stelios T ST
Scientific reports 20190705 1
Neural crest (NC) cells are multipotent stem cells that arise from the embryonic ectoderm, delaminate from the neural tube in early vertebrate development and migrate throughout the developing embryo, where they differentiate into various cell lineages. Here we show that multipotent and functional NC cells can be derived by induction with a growth factor cocktail containing FGF2 and IGF1 from cultures of human inter-follicular keratinocytes (KC) isolated from elderly donors. Adult NC cells exhib ...[more]