Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation.
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ABSTRACT:
SUBMITTER: Le Roy CI
PROVIDER: S-EPMC6611773 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Publications
Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation.
Le Roy Caroline I CI Bowyer Ruth C E RCE Castillo-Fernandez Juan E JE Pallister Tess T Menni Cristina C Steves Claire J CJ Berry Sarah E SE Spector Tim D TD Bell Jordana T JT
Scientific reports 20190705 1
Both gut microbiota and diet have been shown to impact visceral fat mass (VFM), a major risk factor for cardiometabolic disease, but their relative contribution has not been well characterised. We aimed to estimate and separate the effect of gut microbiota composition from that of nutrient intake on VFM in 1760 older female twins. Through pairwise association analyses, we identified 93 operational taxonomic units (OTUs) and 10 nutrients independently linked to VFM (FDR < 5%). Conditional analyse ...[more]
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