Ontology highlight
ABSTRACT:
SUBMITTER: Chekan JR
PROVIDER: S-EPMC6613135 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Chekan Jonathan R JR Ongpipattanakul Chayanid C Wright Terry R TR Zhang Bo B Bollinger J Martin JM Rajakovich Lauren J LJ Krebs Carsten C Cicchillo Robert M RM Nair Satish K SK
Proceedings of the National Academy of Sciences of the United States of America 20190617 27
The synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D) is an active ingredient of thousands of commercial herbicides. Multiple species of bacteria degrade 2,4-D via a pathway initiated by the Fe(II) and α-ketoglutarate (Fe/αKG)-dependent aryloxyalkanoate dioxygenases (AADs). Recently, genes encoding 2 AADs have been deployed commercially in herbicide-tolerant crops. Some AADs can also inactivate chiral phenoxypropionate and aryloxyphenoxypropionate (AOPP) herbicides, albeit with varying subs ...[more]