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Comment on 'Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age'.

ABSTRACT: Ruby et al. recently analyzed historical lifespan data on more than 3200 naked mole-rats, collected over a total observation period of about 38 years (Ruby et al., 2018). They report that mortality hazards do not seem to increase across the full range of their so-far-observed lifespan, and conclude that this defiance of Gompertz's law 'uniquely identifies the naked mole-rat as a non-aging mammal'. Here, we explain why we believe this conclusion is premature.

SUBMITTER: Dammann P 

PROVIDER: S-EPMC6615855 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Comment on 'Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age'.

Dammann Philip P   Scherag André A   Zak Nikolay N   Szafranski Karol K   Holtze Susanne S   Begall Sabine S   Burda Hynek H   Kestler Hans A HA   Hildebrandt Thomas T   Platzer Matthias M  

eLife 20190709

Ruby et al. recently analyzed historical lifespan data on more than 3200 naked mole-rats, collected over a total observation period of about 38 years (Ruby et al., 2018). They report that mortality hazards do not seem to increase across the full range of their so-far-observed lifespan, and conclude that this defiance of Gompertz's law 'uniquely identifies the naked mole-rat as a non-aging mammal'. Here, we explain why we believe this conclusion is premature. ...[more]

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