Sex Moderates the Effect of Aerobic Exercise on Some Aspects of Cognition in Cognitively Intact Younger and Middle-Age Adults.

ABSTRACT: We recently reported the results of a randomized, parallel-group, observer-masked, community-based clinical trial of 132 cognitively normal individuals aged 20-67 with below median aerobic capacity who were randomly assigned to one of two 6-month, four-times-weekly conditions: aerobic exercise and stretching/toning. We now assessed potential sex moderation on exercise-related changes in aerobic capacity, BMI and cognitive function. There was no sex moderation of the effect of aerobic exercise on aerobic capacity or BMI. We had previously reported an effect of aerobic exercise on executive function that was moderated by age. We found additional moderation by sex, such that in any age range men improved more than women. Processing speed showed significant sex moderation but not significant a

SUBMITTER: Stern Y 

PROVIDER: S-EPMC6617072 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature