Paired-end mappability of transposable elements in the human genome.
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ABSTRACT:
SUBMITTER: Sexton CE
PROVIDER: S-EPMC6617613 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Paired-end mappability of transposable elements in the human genome.
Sexton Corinne E CE Han Mira V MV
Mobile DNA 20190710
Though transposable elements make up around half of the human genome, the repetitive nature of their sequences makes it difficult to accurately align conventional sequencing reads. However, in light of new advances in sequencing technology, such as increased read length and paired-end libraries, these repetitive regions are now becoming easier to align to. This study investigates the mappability of transposable elements with 50 bp, 76 bp and 100 bp paired-end read libraries. With respect to thos ...[more]
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