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Chronic obstructive pulmonary disease in rheumatoid arthritis: a systematic review and meta-analysis.


ABSTRACT: BACKGROUND:The risk and prevalence of chronic obstructive pulmonary disease (COPD) in rheumatoid arthritis (RA) is still obscure. The current study was aimed to systematically review and meta-analyse the risk ratio (RR) and prevalence of COPD in RA. METHODS:A comprehensive systematic review was conducted based on PubMed, Web of Science and Cochrane Library from inception to April 30, 2018. The primary outcome of our study was the RR of COPD in RA patients compared with controls, and secondary was the prevalence of COPD in RA patients. Pooled effect sizes were calculated according to fixed effect model or random effects model depending on heterogeneity. RESULTS:Six and eight studies reported the RR and prevalence of COPD in RA respectively. Compared with controls, RA patients have significant increased risk of incident COPD with pooled RR 1.82 (95% CI?=?1.55 to 2.10, P?

SUBMITTER: Ma Y 

PROVIDER: S-EPMC6617695 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Chronic obstructive pulmonary disease in rheumatoid arthritis: a systematic review and meta-analysis.

Ma Yubo Y   Tong Hui H   Zhang Xu X   Wang Mengmeng M   Yang Jiajia J   Wu Meng M   Han Renfang R   Chen Mengya M   Hu Xingxing X   Yuan Yaping Y   Pan Guixia G   Zou Yanfeng Y   Xu Shengqian S   Pan Faming F  

Respiratory research 20190709 1


<h4>Background</h4>The risk and prevalence of chronic obstructive pulmonary disease (COPD) in rheumatoid arthritis (RA) is still obscure. The current study was aimed to systematically review and meta-analyse the risk ratio (RR) and prevalence of COPD in RA.<h4>Methods</h4>A comprehensive systematic review was conducted based on PubMed, Web of Science and Cochrane Library from inception to April 30, 2018. The primary outcome of our study was the RR of COPD in RA patients compared with controls, a  ...[more]

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