Ontology highlight
ABSTRACT:
SUBMITTER: O'Sullivan SJ
PROVIDER: S-EPMC6619439 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
O'Sullivan Sean J SJ Malahias Evangelia E Park James J Srivastava Ankita A Reyes Beverly A S BAS Gorky Jon J Vadigepalli Rajanikanth R Van Bockstaele Elisabeth J EJ Schwaber James S JS
Frontiers in neuroscience 20190703
Drug-seeking in opioid dependence is due in part to the severe negative emotion associated with the withdrawal syndrome. It is well-established that negative emotional states emerge from activity in the amygdala. More recently, gut microflora have been shown to contribute substantially to such emotions. We measured gene expression in single glia and neurons gathered from the amygdala using laser capture microdissection and simultaneously measured gut microflora in morphine-dependent and withdraw ...[more]