Ontology highlight
ABSTRACT:
SUBMITTER: Smith ST
PROVIDER: S-EPMC6620017 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Smith Sheryl T ST Wickramasinghe Priyankara P Olson Andrew A Loukinov Dmitri D Lin Lan L Deng Joy J Xiong Yanping Y Rux John J Sachidanandam Ravi R Sun Hao H Lobanenkov Victor V Zhou Jumin J
Developmental biology 20090108 2
Insulators or chromatin boundary elements are defined by their ability to block transcriptional activation by an enhancer and to prevent the spread of active or silenced chromatin. Recent studies have increasingly suggested that insulator proteins play a role in large-scale genome organization. To better understand insulator function on the global scale, we conducted a genome-wide analysis of the binding sites for the insulator protein CTCF in Drosophila by Chromatin Immunoprecipitation (ChIP) f ...[more]