Fatigue in Nondialysis Chronic Kidney Disease: Correlates and Association with Kidney Outcomes.

ABSTRACT:

Background

Fatigue, although common and associated with outcomes in dialysis-dependent chronic kidney disease (CKD), has not been studied in nondialysis chronic kidney disease (CKD-ND) patients.

Methods

In this longitudinal cohort of 266 outpatients with CKD-ND stages 2-5, we measured self-reported fatigue on 3 scales-Quick Inventory of Depression Symptomatology-Self Report (QIDS-SR16), Beck Depression Inventory-I (BDI-I), and short form 12 health survey (SF-12) questionnaires and evaluated the prespecified composite of progression to dialysis initiation, death, or hospitalization after 12 months. Logistic and linear regression assessed characteristics associated with fatigue. Survival analysis measured associations of fatigue with outcomes.

Results

Mean age was 64.4

SUBMITTER: Gregg LP 

PROVIDER: S-EPMC6620124 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature