Ontology highlight
ABSTRACT:
SUBMITTER: Orner EP
PROVIDER: S-EPMC6620289 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Orner Erika P EP Zhang Pengchao P Jo Myeong C MC Bhattacharya Somanon S Qin Lidong L Fries Bettina C BC
Communications biology 20190710
<i>Cryptococcus neoformans (Cn)</i> is a deadly fungal pathogen responsible for ~ 180,000 deaths per year and despite effective antifungals, treatment failure and resistance to antifungals are increasingly problematic. Aging and age-related phenotypes are prominent virulence traits that contribute to the resilience of <i>Cn</i> to host responses and antifungals. Traditional methods to study aging in <i>Cn</i> are expensive, inefficient and in need of improvement. Here, we demonstrate the develop ...[more]