Ontology highlight
ABSTRACT:
SUBMITTER: Liefferinckx C
PROVIDER: S-EPMC6620879 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Liefferinckx Claire C Verstockt Bram B Gils Ann A Tops Sophie S Van Moerkercke Wouter W Vermeire Severine S Franchimont Denis D
United European gastroenterology journal 20190324 6
<h4>Background</h4>Very little is known about the impact of the wash-out period on the pharmacokinetics of a second-line biologic.<h4>Objective</h4>The objective of this article is to explore the impact of two different wash-out periods on the pharmacokinetics of vedolizumab and infliximab.<h4>Methods</h4>Patients switching from infliximab to vedolizumab were retrospectively identified. The population was divided into two groups according to wash-out period: <6 weeks or >6 weeks. Vedolizumab and ...[more]