Ontology highlight
ABSTRACT:
SUBMITTER: Ji X
PROVIDER: S-EPMC6622462 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Postepy biochemii 20160101 3
Era (Escherichia coli Ras-like protein), essential for bacterial cell viability, is composed of an N-terminal GTPase domain and a C-terminal KH domain. In bacteria, it is required for the processing of 16S ribosomal RNA (rRNA) and maturation of 30S (small) ribosomal subunit. Era recognizes 10 nucleotides (<sub>1530</sub>GAUCACCUCC<sub>1539</sub>) near the 3' end of 16S rRNA and interacts with helix 45 (h45, nucleotides 1506-1529). GTP binding enables Era to bind RNA, RNA binding stimulates Era's ...[more]