Ontology highlight
ABSTRACT:
SUBMITTER: Swiech L
PROVIDER: S-EPMC6622897 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Swiech Lukasz L Blazejczyk Magdalena M Urbanska Malgorzata M Pietruszka Patrycja P Dortland Bjorn R BR Malik Anna R AR Wulf Phebe S PS Hoogenraad Casper C CC Jaworski Jacek J
The Journal of neuroscience : the official journal of the Society for Neuroscience 20110301 12
Dendritic arbors are compartments of neurons dedicated to receiving synaptic inputs. Their shape is an outcome of both the intrinsic genetic program and environmental signals. The microtubules and actin cytoskeleton are both crucial for proper dendritic morphology, but how they interact is unclear. The present study demonstrates that microtubule plus-end tracking protein CLIP-170 and actin-binding protein IQGAP1 regulate dendrite morphology of rat neurons by coordinating the interaction between ...[more]