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Probing the role of perception in fear generalization.


ABSTRACT: Behavior in novel situations is guided by similarities to previous experiences, a phenomenon known as generalization. Despite the widespread influence of generalization on healthy and pathological behavior, insight into the underlying mechanisms is lacking. It remains unclear whether a failure to notice situational changes contributes to the generalization of learned behavior. We combined a fear conditioning and generalization procedure with a perceptual decision task in humans and found that a failure to perceive a novel stimulus as different from the initial fear-evoking stimulus was associated with increased conditioned responding. These findings demonstrate the potential of a perception-centered approach to better understand (pathological) behavior and its underlying mechanism and are a promising avenue for the development of refined generalization protocols.

SUBMITTER: Zaman J 

PROVIDER: S-EPMC6624264 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Probing the role of perception in fear generalization.

Zaman J J   Struyf D D   Ceulemans E E   Beckers T T   Vervliet B B  

Scientific reports 20190711 1


Behavior in novel situations is guided by similarities to previous experiences, a phenomenon known as generalization. Despite the widespread influence of generalization on healthy and pathological behavior, insight into the underlying mechanisms is lacking. It remains unclear whether a failure to notice situational changes contributes to the generalization of learned behavior. We combined a fear conditioning and generalization procedure with a perceptual decision task in humans and found that a  ...[more]

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