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Comparison of long non?coding RNA expression profiles in human dental follicle cells and human periodontal ligament cells.

ABSTRACT: The dental follicle develops into the periodontal ligament, cementum and alveolar bone. Human dental follicle cells (hDFCs) are the precursor cells of periodontal development. Long non?coding RNAs (lncRNAs) have been revealed to be crucial factors that regulate a variety of biological processes; however, whether lncRNAs serve a role in human periodontal development remains unknown. Therefore, the present study used microarrays to detect the differentially expressed lncRNAs and mRNAs between hDFCs and human periodontal ligament cells (hPDLCs). A total of 845 lncRNAs and 1,012 mRNAs were identified to be differentially expressed in hDFCs and hPDLCs (fold change >2.0 or

SUBMITTER: Wu L

PROVIDER: S-EPMC6625187 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Comparison of long non‑coding RNA expression profiles in human dental follicle cells and human periodontal ligament cells.

Wu Liping L Deng Lidi L Hong Hong H Peng Caixia C Zhang Xueqin X Chen Zhengyuan Z Ling Junqi J

Molecular medicine reports 20190529 2

The dental follicle develops into the periodontal ligament, cementum and alveolar bone. Human dental follicle cells (hDFCs) are the precursor cells of periodontal development. Long non‑coding RNAs (lncRNAs) have been revealed to be crucial factors that regulate a variety of biological processes; however, whether lncRNAs serve a role in human periodontal development remains unknown. Therefore, the present study used microarrays to detect the differentially expressed lncRNAs and mRNAs between hDFC ...[more]

PMID: 31173189

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