Data on docking of phytoconstituents of Actinidia deliciosa on dengue viral targets.

ABSTRACT: Major Phytoconstituents of Actinidia deliciosa were explored for their anti-viral potential against dengue virus (DENV). The docking of these phytoconstituents was performed on 7 viral targets- 4 DENV non structural protein (NS5-SAM binding domain, NS5 RdRp domain, NS3 helicase & NS2B-NS3 protease) and 3 DENV structural proteins (Envelope protein-?-OD domain, stem domain & Domain III). The analysis was done on the basis of binding affinity, type of interactions (bond type and distance) and interaction with amino acids significant in viral replication. The top 5 phytoconstituents with best docking score have been reported.

SUBMITTER: Chandani SR 

PROVIDER: S-EPMC6626881 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature